4 aco DMT

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4-AcO-DMT, also known as O-acetylpsilocin or psilacetin, is a synthetic psychedelic drug that is a derivative of DMT and psilocybin. It is a tryptamine related to other psychedelic compounds like psilocybin and psilocin. 4-AcO-DMT is a synthetic psychedelic 5-Meo-DMT tryptamine with a short history of human use. It is technically illegal in Israel as it is a derivative of DMT. 

4-ACO-DMT (also referred to as O-Acetylpsilocin, 4-Acetoxy-DMT, or Psilacetin) may be a synthetically produced psychedelic tryptamine. it’s the acetylated sort of the psilocybin mushroom alkaloid psilocin and may be a lower homolog of 4-AcO-DET, 4-AcO-MiPT, nd 4-AcO-DiPT. David Nicholas suggested it to be a potentially alternative to psilocybin for pharmacological 4acodmt studies. Since they’re both believed to be prodrugs of psilocin. Its structural similarities to 4aco dmt psilocin and psilocybin leads to a uniform subjective effect profile and therefore the three dmt 4 compounds are often said to feel indistinguishable from one another . this enables 4-AcO-DMT to function as an ideal substitute for psilocybin mushrooms.

4-Aco-DMT

44-ACO-DMT and a number of other other esters of psilocin were originally patented on January 16, 1963, y Sandoz Ltd. via Albert Hofmann & Franz Troxler. Before its release as a gray area compound on the web research chemical market.

4-ACO-DMT ‘s psychedelic effects are believed to return from its efficacy at the 5-HT2A receptor as a partial agonist. However, the role of those interactions and the way they end in the psychedelic experience continues to stay elusive.

DMT, short for dimethyltryptamine, is taken into account by many to be among the foremost powerful psychedelics that we will experience. people that have used DMT report mystical visions that are often far stronger than with other psychedelics. They feel that that they had been taken to alternate realities, interacted with sentient interdimensional beings, and had their worldview changed by visceral experiences that seemed more real than their lifestyle . Although the duration of DMT’s effects is brief — 10-20 minutes — users claim it seems like days, weeks, and even years of experience unfold within that span. But the foremost compelling fact about this highly psychoactive drug is that it stands alone among other entheogens because the just one that’s naturally found and produced within the physical body , a incontrovertible fact that has great implications for its use within the treatment of drug abuse , addiction, and other psychological maladies.

What is 4-Aco-DMT?

In the body, 4-AcO-DMT is assumed to be deacetylated into psilocin during the t-pass metabolism and passes through the liver. This has not been formally proven and is predicated on reports that the majority users cannot tell the difference between these two compounds when ingested to the purpose that they’re often considered as indistinguishable from one another in terms of their subjective effects. There are, however, claims of subjective differences in effect between the acetylated and non-acetylated sorts of psilocin. We’ve had reports that it lasts slightly longer than the psilocin, while others say it takes a shorter time. There are many reports of less bod load and nausea compared to psilocin. The visual distortions produced by the 4-AcO-DMT resembles that produced by the DMT.

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Tactile enhancement – This particular component is probably the foremost overwhelming sensation within everything of the 4- experience. It increases the intensity of tactile sensations to such an awesome extent that it can induce a sensation of sustained and repeatable full body orgasm within every nerve end across the whole body to a degree not found within the other hallucinogen . The experience of this leads to the perception of getting difficulty sustaining the act of breathing. it’s worth noting, however, that this is often not a real or dangerous experience of respiratory depression and is taken into account to be safe.

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• Bodily pressures
• Changes in gravity
• Euphoria
• Motor control loss
• Nausea
• Perception of increased weight
• Pupil dilation
• Skin flushing
• Temperature regulation suppression
• Cognitive effects
• Amnesia
• Analysis enhancement
• Anxiety
• Conceptual thinking
• Delusions
• Subconscious communication
• Emotion enhancement
• Increased music appreciation
• Memory suppression
• Ego death

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The relative toxicity of 4-AcO-DMT and more specifically neurologically is a fortiori low, as is the psilocine: almost no neurotoxicity. But these are only exageration and the reality is that no serious scientific study has been conducted on the subject.

Notably, physical risks including vomiting, loss of consciousness, and seizures, but these are fairly uncommon. As far as we know, nobody has died from taking it nor is it likely to be physically dangerous for most people.

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As with any psychedelic, it should probably be avoided by pregnant or breastfeeding women or anyone prone to seizures. Basically  heart problems, blood pressure problems, or mental health issues like severe anxiety. If only to err on the side of caution given the lack of clinical research.

• Puffs of anxiety

• depersonalization

• hallucinations

• Psychosis crisis

• Tachycardia and hypertension

• Abundant perspiration and hyperthermia

• Tight jaws

• nausea

• Loss of appetite

• Want to resume / Craving