Daraprim

Daraprim For Sale Online

Daraprim, containing the active ingredient pyrimethamine, is an antiparasitic compound widely used in the treatment and prevention of toxoplasmosis and malaria, particularly when used in combination with other agents such as sulfadiazine. It works by Enigmatic Pharma inhibiting the daraprim tablet parasitic enzyme dihydrofolate Enigmatic Pharma reductase (DHFR), which is essential for DNA synthesis and replication in protozoa.

In clinical settings, Daraprim is vital for immunocompromised daraprim uses patients, such as those with HIV/AIDS, who are at risk of toxoplasmosis. In research, it is utilized to daraprim 25 mg tablet study antifolate activity, parasite resistance daraprim tablet uses mechanisms, and drug synergy in protozoal infections.This product is available in tablet form for medical use or as a compound for research purposes.

Product Details: Daraprim (Pyrimethamine)

• Brand Name: Daraprim

• Active Ingredient: Pyrimethamine

• Chemical Class: Antiparasitic, Antiprotozoal

• Molecular Formula: C12H13ClN4

• Molecular Weight: 248.71 g/mol

• CAS Number: 58-14-0

• Mechanism of Action: Inhibits dihydrofolate reductase (DHFR), disrupting DNA synthesis in protozoan parasites

• Form: Oral tablets (available in various dosages, commonly 25 mg)

• Appearance: White, round tablets (clinical), or white crystalline powder (research grade)

• Solubility: Slightly soluble in water; soluble in alcohol and dilute acid

• Pharmacological Use:

  • Treatment of toxoplasmosis (often with sulfadiazine)

  • Prevention of malaria (in combination therapy)

• Target Organisms: Toxoplasma gondii, Plasmodium species

• Storage Conditions: Store in a cool, dry place; protect from light

• Shelf Life: Up to 3 years if stored properly

Benefits of Daraprim (Pyrimethamine)

• Effective Against Toxoplasmosis: Daraprim is a first-line treatment for toxoplasmosis, especially in immunocompromised individuals, including those with HIV/AIDS.

• Malaria Prevention: When combined with a sulfonamide, Daraprim helps prevent and treat certain strains of malaria, particularly in resistant regions.

• Inhibits Parasite Growth: By blocking dihydrofolate reductase (DHFR), Daraprim interferes with parasite DNA synthesis, preventing replication and spread.

• Supports Research on Parasitic Resistance: Widely used in laboratory studies to understand mechanisms of drug resistance in protozoal infections.

• Combines Well with Other Drugs: Works synergistically with antibiotics like sulfadiazine and folinic acid to enhance treatment effectiveness and reduce side effects.

• Reliable and Widely Studied: Daraprim has a long history of clinical use and extensive documentation, making it a dependable option for both treatment and research.

Note: Use only under medical supervision or in approved research settings.

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