Hydromorphone

Buy Hydromorphone Online

Hydromorphone is a potent opioid analgesic used to manage severe pain. It works by altering the way the brain and nervous system respond to discomfort. Commonly prescribed for post-surgical pain, cancer-related pain, or chronic conditions, Hydromorphone offers fast and reliable relief when other painkillers fall short.

We offer Hydromorphone HCL 2mg tablets, hydromorphone tablets, and hydromorphone 4 mg tablets to meet varying treatment needs. The hydromorphone 2mg tablet is ideal for patients who require lower dosage options with consistent results.

Though not derived from cannabis, Hydromorphone shares similarities in targeting pain pathways. As a cannabis expert, we understand the importance of tailored pain management. Combining responsible opioid use with natural alternatives can provide a well-rounded care plan. Always consult your physician before use.

Choose Enigmatic Pharma for reliable, pharmaceutical-grade pain solutions. We ensure discreet delivery and quality assurance with every order.

Product Specification: Hydromorphone

Product Name

• Hydromorphone Hydrochloride

Chemical Information

• Generic Name: Hydromorphone

• Chemical Name: 4,5α-Epoxy-3-hydroxy-17-methylmorphinan-6-one hydrochloride

• Molecular Formula: C17H19NO3·HCl

• Molecular Weight: 321.8 g/mol

• CAS Number: 71-28-1

• ATC Code: N02AA03

Pharmaceutical Form

• Oral Tablets (Immediate and Extended Release)

• Injectable Solution (Intravenous/Subcutaneous/Intramuscular)

• Oral Liquid Solution

• Suppositories

Strengths Available

• Oral Tablets: 2 mg, 4 mg, 8 mg

• Extended Release Tablets: 8 mg, 16 mg, 32 mg

• Injectable Solution: 1 mg/mL, 2 mg/mL, 10 mg/mL

• Oral Solution: 1 mg/mL, 5 mg/5 mL

Indications

Hydromorphone is indicated for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

Mechanism of Action

Hydromorphone binds to opioid receptors in the central nervous system (CNS), primarily the mu-opioid receptor, altering the perception of and response to pain.

Pharmacokinetics

• Absorption: Rapidly absorbed after oral administration

• Bioavailability: ~32% (oral)

• Onset of Action: 15–30 minutes (oral); 5 minutes (IV)

• Peak Plasma Concentration: ~0.5 to 1 hour (oral)

• Half-life: 2–3 hours (immediate release)

• Metabolism: Hepatic (glucuronidation)

• Excretion: Renal (~75% as metabolites)

Storage Conditions

• Store at 20°C to 25°C (68°F to 77°F)

• Protect from moisture and light

• Keep in a secure location due to abuse potential

Packaging

• Blister packs or bottles (oral forms)

• Vials or ampoules (injectable solution)

• Unit dose packaging for hospital use

Regulatory Status

• Controlled Substance: Schedule II (USA)

• Requires strict regulation and recordkeeping

• Approved by FDA, EMA, and other national regulatory agencies for appropriate indications

Warnings and Precautions

• Risk of addiction, abuse, and misuse

• Life-threatening respiratory depression

• Neonatal opioid withdrawal syndrome

• Use with benzodiazepines or other CNS depressants may cause profound sedation or respiratory depression

Adverse Effects

• Common: Nausea, vomiting, dizziness, sedation, constipation

• Serious: Respiratory depression, hypotension, dependence, seizures

Contraindications

• Significant respiratory depression

• Acute or severe bronchial asthma

• Known or suspected gastrointestinal obstruction, including paralytic ileus

• Hypersensitivity to hydromorphone or any component of the formulation

Manufacturer Information

To be provided by the manufacturer/distributor, including facility compliance with Good Manufacturing Practices (GMP).

Product Benefits of Hydromorphone

• Effective Pain Relief
  Hydromorphone is a potent opioid analgesic that provides rapid and powerful relief for moderate to severe pain, making it suitable for post-operative pain, cancer-related pain, and injury-related pain.

• Fast Onset of Action
  It begins to work quickly—often within 15–30 minutes—allowing for timely pain control in acute care settings.

• High Potency
  Hydromorphone is approximately 5–10 times more potent than morphine, enabling effective pain control with smaller doses, which can be advantageous in certain medical situations.

• Multiple Administration Routes
  Available in oral, injectable, and rectal formulations, offering flexible options for different clinical needs and patient conditions (e.g., patients unable to take oral medications).

• Shorter Half-Life for Dose Adjustments
  Its relatively short half-life enables easier titration and adjustment of dosage, which is especially useful in acute pain management and palliative care.

• Reduced Histamine Release Compared to Morphine
  Hydromorphone tends to produce less histamine-related side effects such as itching or flushing, improving patient comfort and tolerability.

• Useful in Opioid Rotation
  An excellent option for opioid rotation in patients who develop tolerance or side effects with other opioids, helping restore effective pain relief.

Take control of your pain—order Hydromorphone today.